The design of Vitality Pearls reveals a most general tonic for the Spleen, Lung and Kidney systems. The classical formula Fuzi Lizhong Wan (Rectify the Middle Pill with Aconite) is perhaps the most typical remedy to restore the yang forces in chronically debilitated patients. As a built-in safety mechanism, Vitality Pearls buffers the exclusive warming properties of Lizhong Wan by including a minimal amount of the bitter/cold herb coptis, while balancing its drying properties with ingredients that moisten the yin of Lung and Stomach. Epimedium and psoralea are added to further strengthen the yang tonic effect, and further serve as guiding herbs to the bone layer. Vitality Pearls, therefore, is not only a most suitable way to achieve the final “recharging” goal in the treatment of chronic debilitating diseases, but represents a constitutional remedy for the common patient type presenting with chronically weak digestion, food allergies, and thyroid and bone issues. In addition, Vitality Pearls represents the most straightforward way to prescribe the restorative herb aconite within the Classical Pearl series, and may even be used from the very beginning in the treatment of yang deficient “Gu syndrome” patients.